What is the market doing?
What the tape says about SYRE
Spyre Therapeutics, Inc. is +514% over the past year while the S&P 500 is +23%: 492 points ahead of the market.
+514%
1-year return · S&P 500 +23%
- vs 200-day average
- +69%
vs 200-day average · a clear uptrend
- RSI (14)
- 35
RSI (14) · neutral
- Below its 52-week high
- −14%
Below its 52-week high
Details›
- Last close2026-08-26
- $93.63
- 1 monthS&P 500 +3.7%
- −6.4%
- 1 yearS&P 500 +23%
- +514%
- 5 yearsS&P 500 +87%
- −39%
- vs 50-day average$93.72
- −0.09%
- 52-week high
- $108.94
- 52-week low
- $14.82
- Annualised volatility
- 69%
- Insider buying, net, 6 monthsForms 3/4/5 to 2026-06-30
- −$401M
| Year | Return |
|---|---|
| 2026 (year to date) | +186% |
| 2025 | +41% |
| 2024 | +8.2% |
| 2023 | +91% |
| 2022 | −91% |
| 2021 | −40% |
| 2020 | +3.0% |
| 2019 | +2.0% |
| 2018 | +38% |
| 2017 | +24% |
| Month | Years | Positive | Average |
|---|---|---|---|
| Jan | 10 | 4 of 10 | +3.5% |
| Feb | 10 | 5 of 10 | +2.9% |
| Mar | 10 | 5 of 10 | +2.2% |
| Apr | 10 | 2 of 10 | −0.99% |
| May | 10 | 5 of 10 | −4.6% |
| Jun | 10 | 5 of 10 | +18% |
| Jul | 11 | 5 of 11 | +0.93% |
| Aug | 11 | 8 of 11 | +9.3% |
| Sep | 10 | 6 of 10 | +1.7% |
| Oct | 10 | 4 of 10 | +11% |
| Nov | 10 | 4 of 10 | +0.50% |
| Dec | 10 | 4 of 10 | −1.9% |
End-of-day closes from IEX; the S&P 500 comparison uses SPY over the same window. Prices are a reference point, not a basis for trading decisions.