SYRESpyre Therapeutics, Inc.

$93.63

Price

$93.63+514%1Y
1M-6.4%1Y+514%

Prices are end-of-day closes. This is a research view, the focus is on the fundamentals, quality and valuation below, not intraday price.

Smart Score

Top tier
10/10
Value91
Quality58
Momentum94
Growth-
Strongest Momentum, weakest Quality · ranked vs Healthcare peers. The five questions below judge the company on its own terms.
What they do

Spyre Therapeutics, Inc. (NASDAQ: SYRE) is a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease (“IBD”) and rheumatic diseases. Spyre’s pipeline includes extended half-life antibodies targeting α4β7, TL1A, and IL-23 in development as monotherapies and pair-wise combinations.

In the company’s own words · 10-K filed Feb 19, 2026 · SEC EDGAR

P/E (TTM)-
Market Cap$7.67B
1Y Return+514%
5Y Return-39%

Business segments

Q2 2022 · $1.3M

The company’s own SEC segment disclosure.

  • Development Fee And Royalty$625.0K50%
  • Development Fee$625.0K50%

For the full year FY2025, revenue was $0 and net income −$155M. Its largest product in 2022-Q2 was Development Fee And Royalty at $625K, 50.0% of the disclosed total, just ahead of Development Fee at 50.0%.

Raw charts

8 series · TTM

As reported to the SEC, without any scoring.