TXG10x Genomics, Inc.

$80.64+518% 1Y

Is the business good?

Mixed

The checks split: nothing decisive, though margins widening.

1 good, 1 neutral, 2 without data
Fundamental health (F-score)4 / 9SEC EDGAR · Dec 31, 2025

Mixed fundamental signals. Nine pass/fail tests of year-over-year health from the filings.

Margin direction, 3 years+17.4 ptsderived

Operating margin has widened over the past few years, the business is getting more profitable per dollar of sales.

Where this answer is blind. The F-score rewards improvement, so an already-elite company can score mid-pack.

How good a business is TXG?

10x Genomics, Inc. earns −26% on the capital it employs against a 9.0% cost of capital, so growth costs more than it returns.

−26%

Return on invested capital · cost of capital 9.0% · 35 points below what the capital costs: growth destroys value

Operating margin
−14%

Operating margin · Health Information Services median 2.8% · 12 months to Q2 2026

Share count, year on year
+4.4%

Share count, year on year · shareholders own a smaller slice than a year ago

R&D as % of revenue
37%

R&D as % of revenue

Operating margin by fiscal year
YearOperating margin
FY2020−179%
FY2021−11%
FY2022−33%
FY2023−43%
FY2024−32%
FY2025−9.5%
Details›
Gross margin12 months to Q2 2026
70%
Operating margin12 months to Q2 2026
−14%
Net margin12 months to Q2 2026
−12%
Free cash flow margin
20%
R&D as % of revenue
37%
Revenue, trailing twelve months
$617M
Free cash flow, trailing twelve months
$121M
Net income, trailing twelve months
−$75M
Return on invested capitaloperating profit after tax ÷ debt + equity − cash
−26%

Margins, capital and share counts from the statements as filed with the SEC; cash conversion is operating cash flow over operating profit after tax.

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