TGTXTG Therapeutics, Inc.

$55.37+71% 1Y

Is the business good?

Mixed

The checks split: margins widening and elite returns on assets, but thin cash backing (0.2×).

2 good, 1 to watch, 1 neutral
Fundamental health (F-score)4 / 9SEC EDGAR · Dec 31, 2025

Mixed fundamental signals. Nine pass/fail tests of year-over-year health from the filings.

Profits arrive as cash0.17×derived · Jun 30, 2026

Operating profit outpaces operating cash flow, watch accruals and working capital. Conversion is improving vs a year ago.

Margin direction, 3 years+33735.2 pts

Profits are tracking sales roughly one-for-one, limited operating leverage either way.

Where ROE comes from36% ROA

High-quality, exceptional returns on the assets themselves, not leverage. ROE 74% = margin × turnover × leverage.

Unless marked, from derived.

Against the whole market›

Percentile against every name Ryufin tracks. Higher is better; the tick marks the middle of the market. Context, not one of the checks above.

FCF conversionbottom 10% of the market
Leverage (Debt/EBITDA)behind 81% of the market

Where this answer is blind. The F-score rewards improvement, so an already-elite company can score mid-pack.

How good a business is TGTX?

TG Therapeutics, Inc. earns 14% on the capital it employs against a 9.0% cost of capital, so the business is worth more the bigger it gets.

14%

Return on invested capital · cost of capital 9.0% · 4.5 points above what the capital costs: growth creates value

Operating margin
17%

Operating margin · Biotechnology median −77% · 12 months to Q2 2026

Cash conversion
0.17×

Cash conversion · −0.75× a year ago · the operating profit has not turned into cash yet

Share count, year on year
−3.3%

Share count, year on year · bought back, each share owns more of the company

Operating margin by fiscal year
YearOperating margin
FY2020−179996%
FY2021−5154%
FY2022−7839%
FY20238.8%
FY202413%
FY202520%
Details›
Gross margin12 months to Q2 2026
82%
Operating margin12 months to Q2 2026
17%
Net margin12 months to Q2 2026
55%
Free cash flow margin
2.2%
R&D as % of revenue
28%
Revenue, trailing twelve months
$800M
Free cash flow, trailing twelve months
$17M
Net income, trailing twelve months
$441M
Return on invested capitaloperating profit after tax ÷ debt + equity − cash
14%

Margins, capital and share counts from the statements as filed with the SEC; cash conversion is operating cash flow over operating profit after tax.