PTGXProtagonist Therapeutics, Inc.

$143.75+131% 1Y

Is it safe?

Mixed

Nothing alarming, nothing pristine: insiders quiet and big price swings.

1 to watch, 1 neutral, 4 without data
Insider conviction-$41.4MSEC EDGAR · Oct 8, 2026

Insiders were net sellers (-$41.4M, 90 days to Oct 8, 2026), selling is often routine.

Drawdown risk57% volderived · Oct 9, 2026

Large price swings, high volatility. Worst drawdown -86% · now 9% below its 52-week high.

Against the whole market›

Percentile against every name Ryufin tracks. Higher is better; the tick marks the middle of the market. Context, not one of the checks above.

Volatilitybehind 74% of the market
Max drawdownbehind 82% of the market

Where this answer is blind. Altman sits structurally low for utilities and pipelines; Beneish runs high for fast growers, since sales growth alone lifts it; banks and REITs are excluded.

Can PTGX take a bad year?

The deepest fall in PTGX's price history on file is −86%; it is 9.4% below its high today.

−86%

Worst drawdown on file · −9.4% today

Annualised volatility
57%

Annualised volatility · roughly twice as jumpy as the market

Details›
Cash and short-term investments
$783M
EBITDA, trailing twelve months
$60M
Operating profit, trailing twelve months
$58M
Annualised volatilitytwo years of daily moves
57%
Worst drawdown on file
−86%
Below its 52-week high
9.4%

Balance sheet from SEC filings; drawdown and volatility from end-of-day closes; Altman Z from the filed statements.

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