IONSIonis Pharmaceuticals, Inc.

$63.37

What is the market doing?

What the tape says about IONS

Ionis Pharmaceuticals, Inc. is +54% over the past year while the S&P 500 is +23%: 32 points ahead of the market.

+54%

1-year return · S&P 500 +23%

vs 200-day average
−14%

vs 200-day average · a clear downtrend

RSI (14)
75

RSI (14) · overbought, bought harder than it has been sold

Below its 52-week high
−27%

Below its 52-week high

2024-08-06$25.51 – $86.50 · dashed line: 200-day average2026-08-26
Details
Last close2026-08-26
$63.37
1 monthS&P 500 +3.7%
+13%
1 yearS&P 500 +23%
+54%
5 yearsS&P 500 +87%
+68%
vs 50-day average$63.60
−0.36%
52-week high
$86.50
52-week low
$40.84
Annualised volatility
48%
Insider buying, net, 6 monthsForms 3/4/5 to 2026-06-30
−$19M
Calendar-year price return
YearReturn
2026 (year to date)−20%
2025+126%
2024−31%
2023+34%
2022+24%
2021−46%
2020−6.4%
2019+12%
2018+7.5%
2017+5.2%
Average return by calendar month, 2016–2026
MonthYearsPositiveAverage
Jan107 of 10+1.5%
Feb105 of 10−0.57%
Mar102 of 10−5.3%
Apr103 of 10+1.6%
May105 of 10−0.26%
Jun108 of 10+5.9%
Jul118 of 11+1.1%
Aug116 of 11+2.4%
Sep105 of 10+5.1%
Oct102 of 10−2.6%
Nov106 of 10+9.7%
Dec104 of 10+0.22%

End-of-day closes from IEX; the S&P 500 comparison uses SPY over the same window. Prices are a reference point, not a basis for trading decisions.