IONSIonis Pharmaceuticals, Inc.

$45.26-26% 1Y

Is it growing?

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Growth is fading: revenue shrinking (−7% year on year) and operating margin narrowing (−13.2 points).

2 to watch, 1 without data
Revenue trend−7% in a year

Trailing-twelve-month revenue vs a year earlier, from the company's own filings. Five-year pace: +5% a year.

Margin direction−13.2 points operating

Trailing-twelve-month operating margin, -73.4% now against -60.2% a year earlier.

All from SEC EDGAR, as of Jun 30, 2026.

Where this answer is blind. These are trailing numbers from the filings, not forecasts: an acquisition or a one-off year can flatter them, so check the quarters.

Is IONS growing?

Ionis Pharmaceuticals, Inc. has grown revenue 12% a year over three years and 4.9% a year over five.

+12%

Revenue growth, 3-year annual rate · Biotechnology median +17% · steady growth, ahead of inflation · compounded from trailing twelve-month revenue

Revenue growth, 5-year rate
+4.9%

Revenue growth, 5-year rate · +12% over three · growth has picked up over the last three years

Years of annual history on file
18

Years of annual history on file · FY2008 to FY2025, as filed

Details›
Revenue FY2021
$810M
Revenue FY2022
$587M
Revenue FY2023
$788M
Revenue FY2024
$705M
Revenue FY2025
$944M

Annual income statements as filed with the SEC.

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