DFTXDefinium Therapeutics, Inc.

$36.91+308% 1Y

What is the market doing?

Mixed

No clear lean: nothing decisive, though heavily shorted (+11% of shares).

1 to watch, 2 neutral
TrendRangeboundderived · Oct 9, 2026

Choppy, but holding above its 200-day average. Price is +43% vs its 200-day average.

Insider conviction−$3.0M (90 days to Oct 8, 2026)SEC EDGAR · Oct 8, 2026

Insiders were net sellers over the 90 days ending Oct 8, 2026; selling is often routine (taxes, diversification).

Short interest11% of sharesFINRA · Sep 15, 2026

Heavily shorted, settled Sep 15, 2026, about a week of normal trading to cover. Up 20% since the previous count, up from 9.8% of shares outstanding three months ago.

Against the whole market›

Percentile against every name Ryufin tracks. Higher is better; the tick marks the middle of the market. Context, not one of the checks above.

1-year returntop 1% of the market
vs 200-day avgtop 6% of the market

Where this answer is blind. Insider selling is often routine (taxes, diversification); only cluster buying is a strong tell.

How DFTX is trading

Definium Therapeutics, Inc. is +308% over the past year while the S&P 500 is +18%: 290 points ahead of the market.

+308%

1-year return · S&P 500 +18%

vs 200-day average
+43%

vs 200-day average · a clear uptrend

RSI (14)
42

RSI (14) · neutral

Below its 52-week high
22%

Below its 52-week high

Sep 18, 2024$4.89 – $47.08 · dashed line: 200-day averageOct 9, 2026
Details›
Last close2026-10-09
$36.91
1 monthS&P 500 +2.7%
−2.2%
1 yearS&P 500 +18%
+308%
5 yearsS&P 500 +88%
+7.5%
vs 50-day average$40.34
−8.5%
52-week high
$47.08
52-week low
$9.54
Annualised volatility
78%
Calendar-year price return
YearReturn
2026 (year to date)+176%
2025+92%
2024+90%
2023+66%
2022−89%
2021−55%
2020+5346%
2019+27%
2018−85%
2017−46%
Average return by calendar month, 2016–2026
MonthYearsPositiveAverage
Jan105 of 10+6.4%
Feb107 of 10+10.0%
Mar105 of 10+104%
Apr106 of 10+2.0%
May103 of 10−3.5%
Jun105 of 10−0.47%
Jul104 of 10−2.4%
Aug104 of 10+35%
Sep103 of 10−4.2%
Oct106 of 10+4.2%
Nov93 of 9+6.8%
Dec106 of 10+11%

End-of-day closes from IEX; the S&P 500 comparison uses SPY over the same window. Prices are a reference point, not a basis for trading decisions.