AMLXAmylyx Pharmaceuticals, Inc.

$28.14+111% 1Y

What is the market doing?

Mixed

No clear lean: nothing decisive, though heavily shorted (+12% of shares).

1 to watch, 2 neutral
TrendRangeboundderived · Oct 9, 2026

Choppy, but holding above its 200-day average. Oversold (RSI 25). Price is +52% vs its 200-day average.

Insider conviction−$4.0M (90 days to Oct 8, 2026)SEC EDGAR · Oct 8, 2026

Insiders were net sellers over the 90 days ending Oct 8, 2026; selling is often routine (taxes, diversification).

Short interest12% of sharesFINRA · Sep 15, 2026

Heavily shorted, settled Sep 15, 2026, more than a week of normal trading to cover, a crowded exit.

Against the whole market›

Percentile against every name Ryufin tracks. Higher is better; the tick marks the middle of the market. Context, not one of the checks above.

1-year returntop 7% of the market
vs 200-day avgtop 4% of the market

Where this answer is blind. Insider selling is often routine (taxes, diversification); only cluster buying is a strong tell.

How AMLX is trading

Amylyx Pharmaceuticals, Inc. is +111% over the past year while the S&P 500 is +18%: 93 points ahead of the market.

+111%

1-year return · S&P 500 +18%

vs 200-day average
+52%

vs 200-day average · a clear uptrend

RSI (14)
25

RSI (14) · oversold, sold harder than it has been bought

Below its 52-week high
29%

Below its 52-week high

Sep 18, 2024$2.88 – $39.67 · dashed line: 200-day averageOct 9, 2026
Details›
Last close2026-10-09
$28.14
1 monthS&P 500 +2.7%
−12%
1 yearS&P 500 +18%
+111%
vs 50-day average$29.84
−5.7%
52-week high
$39.67
52-week low
$11.38
Annualised volatility
78%
Insider buying, net, 6 monthsForms 3/4/5 to 2026-10-08
−$2.9M
Calendar-year price return
YearReturn
2026 (year to date)+133%
2025+220%
2024−74%
2023−60%
Average return by calendar month, 2022–2026
MonthYearsPositiveAverage
Jan43 of 4+7.4%
Feb53 of 5+8.9%
Mar51 of 5−32%
Apr52 of 5−2.0%
May51 of 5−5.8%
Jun54 of 5+32%
Jul55 of 5+19%
Aug53 of 5+17%
Sep53 of 5+15%
Oct53 of 5+16%
Nov43 of 4+1.1%
Dec41 of 4−13%

End-of-day closes from IEX; the S&P 500 comparison uses SPY over the same window. Prices are a reference point, not a basis for trading decisions.

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