NBIXNeurocrine Biosciences, Inc.

$142.40-1.9% 1Y

Is the business good?

Good

A genuinely good business: earnings fully cash-backed (1.5×) and margins widening.

2 good, 2 neutral
Fundamental health (F-score)5 / 9SEC EDGAR · Dec 31, 2025

Mixed fundamental signals. Nine pass/fail tests of year-over-year health from the filings.

Profits arrive as cash1.51×derived · Jun 30, 2026

Operating profit is fully backed by cash. Conversion is worsening vs a year ago.

Margin direction, 3 years+14.7 pts

Positive operating leverage, operating profit is growing faster than sales, so margins widen as the business scales.

Where ROE comes from12% ROA

Margin-driven, fat margins on slower asset turns. ROE 17% = margin × turnover × leverage.

Unless marked, from derived.

Against the whole market›

Percentile against every name Ryufin tracks. Higher is better; the tick marks the middle of the market. Context, not one of the checks above.

FCF conversionmiddle of the market

Where this answer is blind. The F-score rewards improvement, so an already-elite company can score mid-pack.

How good a business is NBIX?

Neurocrine Biosciences, Inc. earns 19% on the capital it employs against a 9.0% cost of capital, so the business is worth more the bigger it gets.

19%

Return on invested capital · cost of capital 9.0% · 10 points above what the capital costs: growth creates value

Operating margin
24%

Operating margin · Drug Manufacturers - Specialty & Generic median 11% · 12 months to Q2 2026

Cash conversion
1.51×

Cash conversion · 1.73× a year ago · operating cash flow covers the operating profit after tax

Share count, year on year
+3.2%

Share count, year on year · shareholders own a smaller slice than a year ago

Operating margin by fiscal year
YearOperating margin
FY202016%
FY20219.0%
FY202217%
FY202313%
FY202424%
FY202522%
Details›
Gross margin12 months to Q2 2026
98%
Operating margin12 months to Q2 2026
24%
Net margin12 months to Q2 2026
21%
Free cash flow margin
26%
R&D as % of revenue
34%
Revenue, trailing twelve months
$3.37B
Free cash flow, trailing twelve months
$866M
Net income, trailing twelve months
$706M
Return on invested capitaloperating profit after tax ÷ debt + equity − cash
19%

Margins, capital and share counts from the statements as filed with the SEC; cash conversion is operating cash flow over operating profit after tax.