LXRXLexicon Pharmaceuticals, Inc.

$1.67+40% 1Y

Is the business good?

Mixed

The checks split: nothing decisive, though margins widening.

1 good, 1 neutral, 2 without data
Fundamental health (F-score)4 / 9SEC EDGAR · Dec 31, 2025

Mixed fundamental signals. Nine pass/fail tests of year-over-year health from the filings.

Margin direction, 3 years+76718.2 ptsderived

Operating margin has widened over the past few years, the business is getting more profitable per dollar of sales.

Where this answer is blind. The F-score rewards improvement, so an already-elite company can score mid-pack.

How good a business is LXRX?

Lexicon Pharmaceuticals, Inc. keeps −131% of every revenue dollar as operating profit, against −77% for the median Biotechnology name.

−131%

Operating margin · Biotechnology median −77% · 12 months to Q2 2026

Share count, year on year
+20%

Share count, year on year · shareholders own a smaller slice than a year ago

R&D as % of revenue
145%

R&D as % of revenue

Gross margin
99%

Gross margin

Operating margin by fiscal year
YearOperating margin
FY2020−199%
FY2021−29225%
FY2022−72489%
FY2023−14265%
FY2024−634%
FY2025−98%
Details›
Gross margin12 months to Q2 2026
99%
Operating margin12 months to Q2 2026
−131%
Net margin12 months to Q2 2026
−147%
R&D as % of revenue
145%
Revenue, trailing twelve months
$41M
Net income, trailing twelve months
−$61M

Margins, capital and share counts from the statements as filed with the SEC; cash conversion is operating cash flow over operating profit after tax.