LXRXLexicon Pharmaceuticals, Inc.

$2.32

Is the business good?

How good a business is LXRX?

Lexicon Pharmaceuticals, Inc. earns −23% on the capital it employs against a 9.0% cost of capital, so growth costs more than it returns.

−23%

Return on invested capital · cost of capital 9.0% · 32 points below what the capital costs: growth destroys value

Operating margin
−35%

Operating margin · Biotechnology median −72% · 12 months to Q1 2026

Share count, year on year
+11%

Share count, year on year · shareholders own a smaller slice than a year ago

R&D as % of revenue
84%

R&D as % of revenue

Operating margin by fiscal year
YearOperating margin
FY2020−199%
FY2021−29225%
FY2022−72489%
FY2023−14265%
FY2024−634%
FY2025−98%
Details
Gross margin12 months to Q1 2026
99%
Operating margin12 months to Q1 2026
−35%
Net margin12 months to Q1 2026
−37%
R&D as % of revenue
84%
Revenue, trailing twelve months
$70M
Net income, trailing twelve months
−$26M
Return on invested capitaloperating profit after tax ÷ debt + equity − cash
−23%

Margins, capital and share counts from the statements as filed with the SEC; cash conversion from the cash flow statement.