KYMRKymera Therapeutics, Inc.

$112.32+129% 1Y

Is the business good?

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More warning than reassurance: 3 of 9 health tests passed and margins compressing.

2 to watch, 2 without data
Fundamental health (F-score)3 / 9SEC EDGAR · Dec 31, 2025

Weak, deteriorating fundamentals. Nine pass/fail tests of year-over-year health from the filings.

Margin direction, 3 years−1417.2 ptsderived

Operating margin has narrowed over the past few years, profitability per dollar of sales is eroding.

Where this answer is blind. The F-score rewards improvement, so an already-elite company can score mid-pack.

How good a business is KYMR?

Kymera Therapeutics, Inc. earns −34% on the capital it employs against a 9.0% cost of capital, so growth costs more than it returns.

−34%

Return on invested capital · cost of capital 9.0% · 43 points below what the capital costs: growth destroys value

Operating margin
−334%

Operating margin · Biotechnology median −77% · 12 months to Q2 2026

Share count, year on year
+22%

Share count, year on year · shareholders own a smaller slice than a year ago

R&D as % of revenue
358%

R&D as % of revenue

Operating margin by fiscal year
YearOperating margin
FY2020−136%
FY2021−138%
FY2022−344%
FY2023−211%
FY2024−556%
FY2025−891%
Details›
Gross margin12 months to Q2 2026
0.00%
Operating margin12 months to Q2 2026
−334%
Net margin12 months to Q2 2026
−285%
Free cash flow margin
−227%
R&D as % of revenue
358%
Revenue, trailing twelve months
$105M
Free cash flow, trailing twelve months
−$238M
Net income, trailing twelve months
−$300M
Return on invested capitaloperating profit after tax ÷ debt + equity − cash
−34%

Margins, capital and share counts from the statements as filed with the SEC; cash conversion is operating cash flow over operating profit after tax.

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