AZN vs LLY

AstraZeneca PLC and Lilly (Eli), both Healthcare

Lilly (Eli) is the larger company at $980B against $271B. On trailing earnings AZN is the cheaper of the two at a P/E of 27.4 against 39.9, a gap that is only a bargain if the two are growing at similar rates. Over the past year LLY returned +61% against +13% for AZN.

AstraZeneca PLC and Lilly (Eli)compared on valuation, return and Ryufin’s Smart Score
FigureAZNLLY
Last close$166$1190
Market cap$271B$980B
Trailing P/Elower is cheaper for the same earnings, not automatically better27.439.9
Dividend yieldn/a0.5%
1-year return+13%+61%
5-year return+61%+412%
Ryufin Smart Scoresector-relative, 1–109/109/10

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

AstraZeneca PLC

Revenue of $31B in H2 2025, net income $4.9B.

Lilly (Eli)

Revenue of $23B in Q2 2026, net income $7.1B. Its largest reported line is Cardiometabolic Health, 47% of the disclosed total.

Open these two in the interactive comparison to add more names, change the period or read the correlation.