AZN vs LLY

AstraZeneca PLC and Lilly (Eli), both Healthcare

Lilly (Eli) is the larger company at $980B against $288B. On trailing earnings AZN is the cheaper of the two at a P/E of 26.2 against 39.5, a gap that is only a bargain if the two are growing at similar rates. Over the past year LLY returned +55% against +5.4% for AZN. The RyuScore puts LLY ahead, 63 against 60 out of 100.

AstraZeneca PLC and Lilly (Eli) compared on valuation, return and the RyuScore
FigureAZNLLY
Last close$159$1179
Market cap$288B$980B
Trailing P/Elower is cheaper for the same earnings, not automatically better26.239.5
Dividend yieldn/a0.5%
1-year return+5.4%+55%
5-year return+57%+418%
RyuScoresector-relative, 1–1060/10063/100

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

AstraZeneca PLC

Revenue of $31B in H2 2025, net income $4.9B.

Lilly (Eli)

Revenue of $23B in Q2 2026, net income $7.1B. Its largest reported line is Cardiometabolic Health, 47% of the disclosed total.

Open these two in the interactive comparison to add more names, change the period or see the correlation.