AZN vs NVS

AstraZeneca PLC and Novartis AG, both Healthcare

Novartis AG is the larger company at $296B against $288B. On trailing earnings NVS is the cheaper of the two at a P/E of 21.2 against 26.2, a gap that is only a bargain if the two are growing at similar rates. Over the past year NVS returned +20% against +5.4% for AZN. The RyuScore puts NVS ahead, 74 against 60 out of 100.

AstraZeneca PLC and Novartis AG compared on valuation, return and the RyuScore
FigureAZNNVS
Last close$159$144
Market cap$288B$296B
Trailing P/Elower is cheaper for the same earnings, not automatically better26.221.2
1-year return+5.4%+20%
5-year return+57%+103%
RyuScoresector-relative, 1–1060/10074/100

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

AstraZeneca PLC

Revenue of $31B in H2 2025, net income $4.9B.

Novartis AG

Revenue of $27B in H2 2025, net income $6.3B.

Open these two in the interactive comparison to add more names, change the period or see the correlation.