ABBV vs AZN

AbbVie and AstraZeneca PLC, both Healthcare

AbbVie is the larger company at $382B against $271B. On trailing earnings AZN is the cheaper of the two at a P/E of 27.4 against 74.3, a gap that is only a bargain if the two are growing at similar rates. Over the past year ABBV returned +37% against +13% for AZN. Ryufin's sector-relative Smart Score puts AZN ahead, 9/10 against 6/10.

AbbVie and AstraZeneca PLCcompared on valuation, return and Ryufin’s Smart Score
FigureABBVAZN
Last close$263$166
Market cap$382B$271B
Trailing P/Elower is cheaper for the same earnings, not automatically better74.327.4
Dividend yield2.5%n/a
1-year return+37%+13%
5-year return+170%+61%
Ryufin Smart Scoresector-relative, 1–106/109/10

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

AbbVie

Revenue of $17B in Q2 2026, net income $3.6B. Its largest reported line is SKYRIZI, 36% of the disclosed total.

AstraZeneca PLC

Revenue of $31B in H2 2025, net income $4.9B.

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