AZN vs NVO

AstraZeneca PLC and Novo Nordisk A/S, both Healthcare

AstraZeneca PLC is the larger company at $288B against $211B. Over the past year AZN returned +5.4% against -35% for NVO. The RyuScore puts NVO ahead, 88 against 60 out of 100.

AstraZeneca PLC and Novo Nordisk A/S compared on valuation, return and the RyuScore
FigureAZNNVO
Last close$159$38.62
Market cap$288B$211B
Trailing P/Elower is cheaper for the same earnings, not automatically better26.2n/a
1-year return+5.4%-35%
5-year return+57%-15%
RyuScoresector-relative, 1–1060/10088/100

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

AstraZeneca PLC

Revenue of $31B in H2 2025, net income $4.9B.

Novo Nordisk A/S

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