AMGN vs AZN

Amgen and AstraZeneca PLC, both Healthcare

AstraZeneca PLC is the larger company at $288B against $182B. On trailing earnings AMGN is the cheaper of the two at a P/E of 25.8 against 26.2, a gap that is only a bargain if the two are growing at similar rates. Over the past year AMGN returned +54% against +5.4% for AZN. The RyuScore puts AMGN ahead, 66 against 60 out of 100.

Amgen and AstraZeneca PLC compared on valuation, return and the RyuScore
FigureAMGNAZN
Last close$415$159
Market cap$182B$288B
Trailing P/Elower is cheaper for the same earnings, not automatically better25.826.2
Dividend yield2.4%n/a
1-year return+54%+5.4%
5-year return+122%+57%
RyuScoresector-relative, 1–1066/10060/100

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

Amgen

Revenue of $10B in Q2 2026, net income $2.4B. Its largest reported line is Other Products, 17% of the disclosed total.

AstraZeneca PLC

Revenue of $31B in H2 2025, net income $4.9B.

Open these two in the interactive comparison to add more names, change the period or see the correlation.