AMGN vs MRK

Amgen and Merck & Co., both Healthcare

Merck & Co. is the larger company at $281B against $182B. On trailing earnings AMGN is the cheaper of the two at a P/E of 25.8 against 115.5, a gap that is only a bargain if the two are growing at similar rates. Over the past year MRK returned +83% against +54% for AMGN. The RyuScore puts MRK ahead, 78 against 66 out of 100.

Amgen and Merck & Co. compared on valuation, return and the RyuScore
FigureAMGNMRK
Last close$415$146
Market cap$182B$281B
Trailing P/Elower is cheaper for the same earnings, not automatically better25.8115.5
Dividend yield2.4%2.3%
1-year return+54%+83%
5-year return+122%+132%
RyuScoresector-relative, 1–1066/10078/100

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

Amgen

Revenue of $10B in Q2 2026, net income $2.4B. Its largest reported line is Other Products, 17% of the disclosed total.

Merck & Co.

Revenue of $17B in Q2 2026, net income null. Its largest reported line is Keytruda, 49% of the disclosed total.

Open these two in the interactive comparison to add more names, change the period or see the correlation.