AMGN vs PFE

Amgen and Pfizer, both Healthcare

Amgen is the larger company at $182B against $144B. On trailing earnings AMGN is the cheaper of the two at a P/E of 25.8 against 37.2, a gap that is only a bargain if the two are growing at similar rates. Over the past year AMGN returned +54% against +23% for PFE. The RyuScore puts AMGN ahead, 66 against 61 out of 100.

Amgen and Pfizer compared on valuation, return and the RyuScore
FigureAMGNPFE
Last close$415$28.27
Market cap$182B$144B
Trailing P/Elower is cheaper for the same earnings, not automatically better25.837.2
Dividend yield2.4%6.2%
1-year return+54%+23%
5-year return+122%-19%
RyuScoresector-relative, 1–1066/10061/100

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

Amgen

Revenue of $10B in Q2 2026, net income $2.4B. Its largest reported line is Other Products, 17% of the disclosed total.

Pfizer

Revenue of $15B in Q2 2026, net income null. Its largest reported line is Eliquis, 16% of the disclosed total.

Open these two in the interactive comparison to add more names, change the period or see the correlation.