AZN vs JNJ

AstraZeneca PLC and Johnson & Johnson, both Healthcare

Johnson & Johnson is the larger company at $550B against $288B. On trailing earnings AZN is the cheaper of the two at a P/E of 26.2 against 30.3, a gap that is only a bargain if the two are growing at similar rates. Over the past year JNJ returned +53% against +5.4% for AZN. The RyuScore puts JNJ ahead, 69 against 60 out of 100.

AstraZeneca PLC and Johnson & Johnson compared on valuation, return and the RyuScore
FigureAZNJNJ
Last close$159$261
Market cap$288B$550B
Trailing P/Elower is cheaper for the same earnings, not automatically better26.230.3
Dividend yieldn/a2.0%
1-year return+5.4%+53%
5-year return+57%+80%
RyuScoresector-relative, 1–1060/10069/100

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

AstraZeneca PLC

Revenue of $31B in H2 2025, net income $4.9B.

Johnson & Johnson

Revenue of $25B in Q2 2026, net income $5.5B. Its largest reported line is DARZALEX, 19% of the disclosed total.

Open these two in the interactive comparison to add more names, change the period or see the correlation.