AZN vs JNJ

AstraZeneca PLC and Johnson & Johnson, both Healthcare

Johnson & Johnson is the larger company at $550B against $271B. On trailing earnings AZN is the cheaper of the two at a P/E of 27.4 against 31.3, a gap that is only a bargain if the two are growing at similar rates. Over the past year JNJ returned +62% against +13% for AZN.

AstraZeneca PLC and Johnson & Johnsoncompared on valuation, return and Ryufin’s Smart Score
FigureAZNJNJ
Last close$166$270
Market cap$271B$550B
Trailing P/Elower is cheaper for the same earnings, not automatically better27.431.3
Dividend yieldn/a1.9%
1-year return+13%+62%
5-year return+61%+81%
Ryufin Smart Scoresector-relative, 1–109/109/10

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

AstraZeneca PLC

Revenue of $31B in H2 2025, net income $4.9B.

Johnson & Johnson

Revenue of $25B in Q2 2026, net income $5.5B. Its largest reported line is DARZALEX, 19% of the disclosed total.

Open these two in the interactive comparison to add more names, change the period or read the correlation.