VRTXVertex Pharmaceuticals

$510.18+32% 1Y

Is the price fair?

Fair

Neither cheap nor expensive: growth expectations in line with delivery and in its normal P/E range.

3 neutral
What the price assumes~+11% a yearderived · Jun 30, 2026

Priced for ~11% a year FCF growth. Roughly in line with its three-year revenue growth of 10% a year.

Vs its own P/E rangemid-range for this companyderived

In its normal range: P/E 29.7 vs a 27.2 median over 34 quarters (+9% vs median).

Vs sector (EV/EBIT)25.9×derived · Dec 31, 2025

Sector median 22.6× across 130 covered peers. EV/EBIT counts debt as part of the price, so a cash-rich and a borrowed company can be compared on the same footing.

Against the whole market›

Percentile against every name Ryufin tracks. Higher is better; the tick marks the middle of the market. Context, not one of the checks above.

P/E (valuation)behind 67% of the market
FCF yieldbehind 67% of the market

Where this answer is blind. The growth-implied estimate assumes a fixed discount rate; capital-heavy sectors look structurally rich on it.

What VRTX's price assumes

Vertex Pharmaceuticals trades at 29.7× earnings against 18.8× for the median Biotechnology name, more expensive than its own group.

29.7

Trailing P/E · Biotechnology median 18.8 · 1.58× the median: the market pays up for this one

Price / sales
9.55

Price / sales · today's price, fiscal year to Dec 31, 2025

Free cash flow yield
3.3%

Free cash flow yield · Biotechnology median 3.6%

Growth the price implies
+11%

Growth the price implies · The price pays for +11% free cash flow growth a year for a decade; the business has delivered −0.71% a year over the last three.

Details›
Price / booktoday's price, fiscal year to Dec 31, 2025
6.14
EV / EBITtoday's price, fiscal year to Dec 31, 2025
25.9
EV / salestoday's price, fiscal year to Dec 31, 2025
9.00
Healthcare median P/E509 names
26.2
Biotechnology median P/E244 names
18.8
Free cash flow, trailing twelve months
$3.80B
Market capitalisation
$114.6B
3-year revenue growth
+9.8%
3-year free cash flow growth
−0.71%
What the market has paid for these earnings: 34 quarters of its own multiple × $17.17 of trailing earnings per share
MethodPer share
Its own P/E history, lower quartile$393.01
Its own P/E history, median$466.35
Its own P/E history, upper quartile$688.40
52-week range$376.62 – $558.12
Today$510.18

Multiples from SEC filings and end-of-day closes; implied growth from a reverse discounted cash flow. Group medians across the names Ryufin tracks.