SEPNSepterna, Inc.

$38.32+144% 1Y

Who owns SEPN

151 institutions reported holding SEPN for 2026Q2, together 106% of the company, more than the 123 a quarter earlier.

151

Institutions reporting a position · as of 2026Q2 · up from 123 the quarter before

Shares held by institutions
47.2M

Shares held by institutions · 106% of the company · long US equity positions only, as reported on Form 13F

Reported value
$1.58B

Reported value · at Jun 30, 2026 prices, not today's

Top 5 holders
56%

Top 5 holders · of the whole company, between five filers

Details›
Reporting quarter2026-06-30
2026Q2
Quarters on record
7
New positions
46
Positions exited
18
Added to
46
Reduced
31
Top 10 holdersof the company
78%
Shares sold shortsettled Sep 15, 2026
2.9M
Short interestof shares outstanding
6.5%
Days to coverat the average daily volume
9.5
Change in the short positionsince the Aug 31, 2026 count
+6.5%
Institutional ownership by quarter, 2024Q4 to 2026Q2
QuarterFilersSharesReported value
2026Q215147.2M$1.58B
2026Q112345.7M$1.10B
2025Q412045.6M$1.27B
2025Q38244.5M$838M
2025Q28944.4M$470M
2025Q17145.3M$262M
2024Q47144.1M$1.01B
Largest reported holders, 2026Q2
HolderShares% of companyValue
RA CAPITAL MANAGEMENT, L.P.7.0M16%$234M
TRV GP V, LLC6.2M14%$208M
Driehaus Capital Management LLC4.4M9.9%$148M
TRV GP VI, LLC4.2M9.4%$141M
SAMSARA BIOCAPITAL, LLC3.1M7.0%$105M
GOLDMAN SACHS GROUP INC3.1M6.8%$103M
BlackRock Inc.1.9M4.3%$65M
Siren, L.L.C.1.9M4.2%$64M
VANGUARD GROUP INC1.6M3.7%$55M
Avoro Capital Advisors LLC1.3M3.0%$45M
Short interest by settlement date, Aug 29, 2025 to Sep 15, 2026
SettlementShares shortOf shares outstandingDays to cover
Sep 15, 20262.9M6.5%9.5
Aug 31, 20262.7M6.1%7.7
Aug 14, 20262.9M6.4%5.1
Jul 31, 20263.5M7.8%14.2
Jul 15, 20263.4M7.5%5.7
Jun 30, 20263.2M7.0%5.3
Jun 15, 20262.7M6.0%7.8
May 29, 20262.6M5.8%9.5
May 15, 20262.4M5.3%7.4
Apr 30, 20262.1M4.6%5.4
Apr 15, 20262.5M5.5%8.1
Mar 31, 20262.2M4.9%8.7

SEC Form 13F data sets (DERA bulk files). 13F is quarterly, filed up to 45 days late, and covers long US equity positions only, no shorts, no derivatives, nothing held below the reporting threshold. The short position is FINRA's consolidated count for each twice-monthly settlement date, as a share of shares outstanding.

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