AXSM vs JAZZ

Axsome Therapeutics, Inc. and Jazz Pharmaceuticals plc, both Healthcare

Jazz Pharmaceuticals plc is the larger company at $14B against $13B. Over the past year JAZZ returned +123% against +99% for AXSM. Ryufin's sector-relative Smart Score puts AXSM ahead, 9/10 against 6/10.

Axsome Therapeutics, Inc. and Jazz Pharmaceuticals plccompared on valuation, return and Ryufin’s Smart Score
FigureAXSMJAZZ
Last close$207$249
Market cap$13B$14B
1-year return+99%+123%
5-year return+312%+46%
Ryufin Smart Scoresector-relative, 1–109/106/10

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

Axsome Therapeutics, Inc.

Revenue of $218M in Q2 2026, net income null. Its largest reported line is Royalty And Milestone, 66% of the disclosed total.

Jazz Pharmaceuticals plc

Revenue of $1.1B in Q1 2026, net income $293M. Its largest reported line is Oncology, 31% of the disclosed total.

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