AXSM vs MDGL

Axsome Therapeutics, Inc. and Madrigal Pharmaceuticals, Inc., both Healthcare

Axsome Therapeutics, Inc. is the larger company at $12B against $12B. Over the past year AXSM returned +45% against +7.3% for MDGL. The RyuScore puts AXSM ahead, 18 against 11 out of 100.

Axsome Therapeutics, Inc. and Madrigal Pharmaceuticals, Inc. compared on valuation, return and the RyuScore
FigureAXSMMDGL
Last close$168$472
Market cap$12B$12B
1-year return+45%+7.3%
5-year return+544%+496%
RyuScoresector-relative, 1–1018/10011/100

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

Axsome Therapeutics, Inc.

Revenue of $218M in Q2 2026, net income null. Its largest reported line is Royalty And Milestone, 66% of the disclosed total.

Madrigal Pharmaceuticals, Inc.

Revenue of $364M in Q2 2026, net income null.

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