AXSM vs MDGL
Axsome Therapeutics, Inc. and Madrigal Pharmaceuticals, Inc., both Healthcare
Axsome Therapeutics, Inc. is the larger company at $13B against $12B. Over the past year AXSM returned +99% against +57% for MDGL. Ryufin's sector-relative Smart Score puts AXSM ahead, 9/10 against 5/10.
| Figure | AXSM | MDGL |
|---|---|---|
| Last close | $207 | $539 |
| Market cap | $13B | $12B |
| 1-year return | +99% | +57% |
| 5-year return | +312% | +513% |
| Ryufin Smart Scoresector-relative, 1–10 | 9/10 | 5/10 |
Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.
Axsome Therapeutics, Inc.
Revenue of $218M in Q2 2026, net income null. Its largest reported line is Royalty And Milestone, 66% of the disclosed total.
Madrigal Pharmaceuticals, Inc.
Revenue of $364M in Q2 2026, net income null.
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