AXSM vs IONS
Axsome Therapeutics, Inc. and Ionis Pharmaceuticals, Inc., both Healthcare
Ionis Pharmaceuticals, Inc. is the larger company at $13B against $12B. Over the past year AXSM returned +45% against -26% for IONS. The RyuScore puts AXSM ahead, 18 against 17 out of 100.
| Figure | AXSM | IONS |
|---|---|---|
| Last close | $168 | $45.26 |
| Market cap | $12B | $13B |
| 1-year return | +45% | -26% |
| 5-year return | +544% | +25% |
| RyuScoresector-relative, 1–10 | 18/100 | 17/100 |
Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.
Axsome Therapeutics, Inc.
Revenue of $218M in Q2 2026, net income null. Its largest reported line is Royalty And Milestone, 66% of the disclosed total.
Ionis Pharmaceuticals, Inc.
Revenue of $268M in Q2 2026, net income null. Its largest reported line is Royalty, 28% of the disclosed total.
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