ARGX vs VRTX

argenx SE and Vertex Pharmaceuticals, both Healthcare

Vertex Pharmaceuticals is the larger company at $115B against $56B. On trailing earnings VRTX is the cheaper of the two at a P/E of 29.7 against 42.2, a gap that is only a bargain if the two are growing at similar rates. Over the past year VRTX returned +32% against +12% for ARGX. The RyuScore puts VRTX ahead, 59 against 11 out of 100.

argenx SE and Vertex Pharmaceuticals compared on valuation, return and the RyuScore
FigureARGXVRTX
Last close$825$510
Market cap$56B$115B
Trailing P/Elower is cheaper for the same earnings, not automatically better42.229.7
1-year return+12%+32%
5-year return+156%+168%
RyuScoresector-relative, 1–1011/10059/100

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

argenx SE

Revenue of $2.5B in H2 2025, net income $877M.

Vertex Pharmaceuticals

Revenue of $3.3B in Q2 2026, net income $1.1B. Its largest reported line is TRIKAFTAKAFTRIO, 75% of the disclosed total.

Open these two in the interactive comparison to add more names, change the period or see the correlation.