ARGX vs RPRX

argenx SE and Royalty Pharma plc, both Healthcare

argenx SE is the larger company at $55B against $30B. On trailing earnings RPRX is the cheaper of the two at a P/E of 32.9 against 53.5, a gap that is only a bargain if the two are growing at similar rates. Over the past year RPRX returned +71% against +56% for ARGX.

argenx SE and Royalty Pharma plccompared on valuation, return and Ryufin’s Smart Score
FigureARGXRPRX
Last close$1047$61.80
Market cap$55B$30B
Trailing P/Elower is cheaper for the same earnings, not automatically better53.532.9
1-year return+56%+71%
5-year return+239%+87%
Ryufin Smart Scoresector-relative, 1–107/107/10

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

argenx SE

Revenue of $2.5B in H2 2025, net income $877M.

Royalty Pharma plc

Revenue of $674M in Q2 2026, net income $18M. Its largest reported line is Financial Royalty Assets, 94% of the disclosed total.

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