ALNY vs ARGX

Alnylam Pharmaceuticals, Inc. and argenx SE, both Healthcare

argenx SE is the larger company at $56B against $39B. On trailing earnings ARGX is the cheaper of the two at a P/E of 42.2 against 118.1, a gap that is only a bargain if the two are growing at similar rates. Over the past year ARGX returned +12% against -49% for ALNY. The RyuScore puts ALNY ahead, 15 against 11 out of 100.

Alnylam Pharmaceuticals, Inc. and argenx SE compared on valuation, return and the RyuScore
FigureALNYARGX
Last close$233$825
Market cap$39B$56B
Trailing P/Elower is cheaper for the same earnings, not automatically better118.142.2
1-year return-49%+12%
5-year return+24%+156%
RyuScoresector-relative, 1–1015/10011/100

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

Alnylam Pharmaceuticals, Inc.

Revenue of $2.5B in H1 2026, net income $370M. Its largest reported line is Amvuttra, 67% of the disclosed total.

argenx SE

Revenue of $2.5B in H2 2025, net income $877M.

Open these two in the interactive comparison to add more names, change the period or see the correlation.