ALNY vs MRNA

Alnylam Pharmaceuticals, Inc. and Moderna, both Healthcare

Alnylam Pharmaceuticals, Inc. is the larger company at $37B against $25B. Over the past year MRNA returned +93% against -45% for ALNY. Ryufin's sector-relative Smart Score puts MRNA ahead, 9/10 against 8/10.

Alnylam Pharmaceuticals, Inc. and Modernacompared on valuation, return and Ryufin’s Smart Score
FigureALNYMRNA
Last close$239$62.96
Market cap$37B$25B
Trailing P/Elower is cheaper for the same earnings, not automatically better121.3n/a
1-year return-45%+93%
5-year return+34%-81%
Ryufin Smart Scoresector-relative, 1–108/109/10

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

Alnylam Pharmaceuticals, Inc.

Revenue of $2.5B in H1 2026, net income $370M. Its largest reported line is Amvuttra, 63% of the disclosed total.

Moderna

Revenue of $145M in Q2 2026, net income null. Its largest reported line is COVID19, 81% of the disclosed total.

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