Which stocks do VTWO and XBI both hold?

105 stocks are in both. The biggest shared positions: ARWR (0.3% of VTWO, 1.1% of XBI), BBIO (0.3% of VTWO, 1.0% of XBI), CYTK (0.3% of VTWO, 1.2% of XBI), PRAX (0.3% of VTWO, 1.3% of XBI), MDGL (0.2% of VTWO, 1.1% of XBI).

VTWOvsXBI

Vanguard Russell 2000 ETF or State Street SPDR S&P Biotech ETF, side by side from their own SEC filings. 7.2% of their stock holdings are the same at the same weight, across 105 stocks in both. VTWO costs 0.06% a year against 0.35% for XBI, $29 a year less on $10,000. Over the last twelve months VTWO returned +43.2% and XBI +91.7%.

7.2%of the two portfolios is the same stocks at the same weight

VTWO7.2% in stocks the other holds too

XBI68% in stocks the other holds too

stocks in bothstocks only in that fundbonds, cash and unmatched shares

The two funds

From each fund's latest N-PORT filing and its prospectus.

VTWOXBIYearly cost0.06%0.35%Net assets$17.5B$10.7BPositions1,957161Last 12 months+43.2%+91.7%3 years, a year+20.3%+24.1%5 years, a year+6.7%+3.3%Largest holdingVanguard 2.4%State 5.9%Main sectorTechnology 18%Healthcare 94%Holdings as ofMay 31, 2026Jun 30, 2026

Returns are total returns with dividends reinvested, from the funds’ own monthly figures; “(price)” marks a fund whose filing record is younger than a year, whose twelve months are its price change. The stronger figure in each row is set in bold. Past returns say what happened, not what will.

Growth of $100

Both funds from September 2019, the first month both report, dividends reinvested.

VTWO$215XBI$171

September 2019May 2026

What they both hold

105 stocks are in both funds: 7.2% of VTWO and 68% of XBI. The biggest shared positions:

Stockin VTWOin XBI

ARWRArrowhead Pharmaceuticals, Inc.0.3%1.1%BBIOBridgeBio Pharma, Inc.0.3%1.0%CYTKCytokinetics, Incorporated0.3%1.2%PRAXPraxis Precision Medicines, Inc.0.3%1.3%MDGLMadrigal Pharmaceuticals, Inc.0.2%1.1%KRYSKrystal Biotech, Inc.0.2%1.1%ALKSAlkermes plc0.2%1.1%PCVXVaxcyte, Inc.0.2%1.2%PTCTPTC Therapeutics, Inc.0.2%1.0%PTGXProtagonist Therapeutics, Inc.0.2%1.1%

Only in VTWO

Its biggest stocks the other fund does not hold.

Only in XBI

Its biggest stocks the other fund does not hold.

More comparisons

IWM vs VTWO SCHA vs VTWO DFAS vs VTWO IWO vs VTWO IWN vs VTWO IBB vs XBI IWO vs XBI VHT vs XBI

From each fund’s Form N-PORT (VTWO: May 2026, XBI: June 2026) and prospectus, via the SEC’s public data sets. Overlap counts only the stocks we can match to a listing: stock by stock, the smaller of the two weights, added up.