EXEL vs MDGL

Exelixis, Inc. and Madrigal Pharmaceuticals, Inc., both Healthcare

Exelixis, Inc. is the larger company at $13B against $12B. Over the past year EXEL returned +49% against +7.3% for MDGL. The RyuScore puts EXEL ahead, 80 against 11 out of 100.

Exelixis, Inc. and Madrigal Pharmaceuticals, Inc. compared on valuation, return and the RyuScore
FigureEXELMDGL
Last close$59.86$472
Market cap$13B$12B
Trailing P/Elower is cheaper for the same earnings, not automatically better18.8n/a
1-year return+49%+7.3%
5-year return+197%+496%
RyuScoresector-relative, 1–1080/10011/100

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

Exelixis, Inc.

Revenue of $629M in Q2 2026, net income $212M. Its largest reported line is Product Gross, 87% of the disclosed total.

Madrigal Pharmaceuticals, Inc.

Revenue of $364M in Q2 2026, net income null.

Open these two in the interactive comparison to add more names, change the period or see the correlation.