EXEL vs JAZZ

Exelixis, Inc. and Jazz Pharmaceuticals plc, both Healthcare

Jazz Pharmaceuticals plc is the larger company at $14B against $13B. Over the past year JAZZ returned +123% against +50% for EXEL. Ryufin's sector-relative Smart Score puts EXEL ahead, 8/10 against 6/10.

Exelixis, Inc. and Jazz Pharmaceuticals plccompared on valuation, return and Ryufin’s Smart Score
FigureEXELJAZZ
Last close$56.07$249
Market cap$13B$14B
Trailing P/Elower is cheaper for the same earnings, not automatically better18.6n/a
1-year return+50%+123%
5-year return+225%+46%
Ryufin Smart Scoresector-relative, 1–108/106/10

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

Exelixis, Inc.

Revenue of $611M in Q1 2026, net income $210M. Its largest reported line is Product Gross, 87% of the disclosed total.

Jazz Pharmaceuticals plc

Revenue of $1.1B in Q1 2026, net income $293M. Its largest reported line is Oncology, 31% of the disclosed total.

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