EXEL vs JAZZ

Exelixis, Inc. and Jazz Pharmaceuticals plc, both Healthcare

Jazz Pharmaceuticals plc is the larger company at $14B against $13B. On trailing earnings JAZZ is the cheaper of the two at a P/E of 14.9 against 18.8, a gap that is only a bargain if the two are growing at similar rates. Over the past year JAZZ returned +70% against +49% for EXEL. The RyuScore puts EXEL ahead, 80 against 48 out of 100.

Exelixis, Inc. and Jazz Pharmaceuticals plc compared on valuation, return and the RyuScore
FigureEXELJAZZ
Last close$59.86$218
Market cap$13B$14B
Trailing P/Elower is cheaper for the same earnings, not automatically better18.814.9
1-year return+49%+70%
5-year return+197%+62%
RyuScoresector-relative, 1–1080/10048/100

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

Exelixis, Inc.

Revenue of $629M in Q2 2026, net income $212M. Its largest reported line is Product Gross, 87% of the disclosed total.

Jazz Pharmaceuticals plc

Revenue of $1.2B in Q2 2026, net income $193M. Its largest reported line is Oncology, 31% of the disclosed total.

Open these two in the interactive comparison to add more names, change the period or see the correlation.