SIONSionna Therapeutics, Inc.

$51.04+193% 1Y

What is the market doing?

Watch

The market is leaning against it: in a downtrend (−85% vs 200-day) and heavily shorted (+10% of shares).

2 to watch, 1 neutral
TrendDowntrendderived · Oct 9, 2026

In a downtrend, below its 50- and 200-day averages. Oversold (RSI 18). Price is −85% vs its 200-day average.

Insider conviction−$21.8M (90 days to Oct 8, 2026)SEC EDGAR · Oct 8, 2026

Insiders were net sellers over the 90 days ending Oct 8, 2026; selling is often routine (taxes, diversification).

Short interest10% of sharesFINRA · Sep 15, 2026

Heavily shorted, settled Sep 15, 2026, about a week of normal trading to cover. Down 7.7% since the previous count, down from 13.2% of shares outstanding three months ago.

Against the whole market›

Percentile against every name Ryufin tracks. Higher is better; the tick marks the middle of the market. Context, not one of the checks above.

1-year returnbottom 1% of the market
vs 200-day avgbottom 1% of the market

Where this answer is blind. Insider selling is often routine (taxes, diversification); only cluster buying is a strong tell.

How SION is trading

Sionna Therapeutics, Inc. is +193% over the past year while the S&P 500 is +18%: 174 points ahead of the market.

+193%

1-year return · S&P 500 +18%

vs 200-day average
−85%

vs 200-day average · a clear downtrend

RSI (14)
18

RSI (14) · oversold, sold harder than it has been bought

Below its 52-week high
90%

Below its 52-week high

Feb 7, 2025$4.50 – $51.04 · dashed line: 200-day averageOct 9, 2026
Details›
Last close2026-10-09
$51.04
1 monthS&P 500 +2.7%
+31%
1 yearS&P 500 +18%
+193%
vs 50-day average$11.96
−59%
52-week high
$51.03
52-week low
$4.50
Annualised volatility
115%
Insider buying, net, 6 monthsForms 3/4/5 to 2026-10-08
−$22M

End-of-day closes from IEX; the S&P 500 comparison uses SPY over the same window. Prices are a reference point, not a basis for trading decisions.

On our screens:Most shorted stocks