RVMD vs VRTX

Revolution Medicines, Inc. and Vertex Pharmaceuticals, both Healthcare

Vertex Pharmaceuticals is the larger company at $115B against $35B. Over the past year RVMD returned +517% against +42% for VRTX. Ryufin's sector-relative Smart Score puts RVMD ahead, 10/10 against 8/10.

Revolution Medicines, Inc. and Vertex Pharmaceuticalscompared on valuation, return and Ryufin’s Smart Score
FigureRVMDVRTX
Last close$216$547
Market cap$35B$115B
Trailing P/Elower is cheaper for the same earnings, not automatically bettern/a31.9
1-year return+517%+42%
5-year return+635%+171%
Ryufin Smart Scoresector-relative, 1–1010/108/10

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

Revolution Medicines, Inc.

Vertex Pharmaceuticals

Revenue of $3.3B in Q2 2026, net income $1.1B. Its largest reported line is TRIKAFTAKAFTRIO, 79% of the disclosed total.

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