REGN vs VRTX

Regeneron Pharmaceuticals and Vertex Pharmaceuticals, both Healthcare

Vertex Pharmaceuticals is the larger company at $115B against $64B. On trailing earnings REGN is the cheaper of the two at a P/E of 20.1 against 31.9, a gap that is only a bargain if the two are growing at similar rates. Over the past year REGN returned +48% against +42% for VRTX. Ryufin's sector-relative Smart Score puts REGN ahead, 9/10 against 8/10.

Regeneron Pharmaceuticals and Vertex Pharmaceuticalscompared on valuation, return and Ryufin’s Smart Score
FigureREGNVRTX
Last close$815$547
Market cap$64B$115B
Trailing P/Elower is cheaper for the same earnings, not automatically better20.131.9
1-year return+48%+42%
5-year return+43%+171%
Ryufin Smart Scoresector-relative, 1–109/108/10

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

Regeneron Pharmaceuticals

Revenue of $4.3B in Q2 2026, net income $1.3B. Its largest reported line is Share Of Profit Losses, 50% of the disclosed total.

Vertex Pharmaceuticals

Revenue of $3.3B in Q2 2026, net income $1.1B. Its largest reported line is TRIKAFTAKAFTRIO, 79% of the disclosed total.

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