ALC vs ISRG

Alcon Inc. and Intuitive Surgical, both Healthcare

Intuitive Surgical is the larger company at $144B against $32B. On trailing earnings ISRG is the cheaper of the two at a P/E of 42.5 against 54.7, a gap that is only a bargain if the two are growing at similar rates. Over the past year ALC returned -15% against -22% for ISRG.

Alcon Inc. and Intuitive Surgicalcompared on valuation, return and Ryufin’s Smart Score
FigureALCISRG
Last close$72.70$370
Market cap$32B$144B
Trailing P/Elower is cheaper for the same earnings, not automatically better54.742.5
1-year return-15%-22%
5-year return+0.3%+12%
Ryufin Smart Scoresector-relative, 1–106/106/10

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

Alcon Inc.

Revenue of $5.3B in H2 2025, net income $454M.

Intuitive Surgical

Revenue of $2.9B in Q2 2026, net income $818M. Its largest reported line is Instrumentsand Accessories, 49% of the disclosed total.

Open these two in the interactive comparison to add more names, change the period or read the correlation.