DGX vs ILMN

Quest Diagnostics and Illumina, Inc., both Healthcare

Illumina, Inc. is the larger company at $27B against $22B. On trailing earnings DGX is the cheaper of the two at a P/E of 24.5 against 51.9, a gap that is only a bargain if the two are growing at similar rates. Over the past year ILMN returned +171% against +28% for DGX. The RyuScore puts DGX ahead, 63 against 36 out of 100.

Quest Diagnostics and Illumina, Inc. compared on valuation, return and the RyuScore
FigureDGXILMN
Last close$231$278
Market cap$22B$27B
Trailing P/Elower is cheaper for the same earnings, not automatically better24.551.9
1-year return+28%+171%
5-year return+65%-36%
RyuScoresector-relative, 1–1063/10036/100

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

Quest Diagnostics

Revenue of $3.0B in Q2 2026, net income $320M. Its largest reported line is Diagnostic Information Services Business, 98% of the disclosed total.

Illumina, Inc.

Revenue of $1.2B in Q2 2026, net income $207M. Its largest reported line is United States And Canada, 56% of the disclosed total.

Open these two in the interactive comparison to add more names, change the period or see the correlation.