ASND vs JAZZ

Ascendis Pharma A/S and Jazz Pharmaceuticals plc, both Healthcare

Ascendis Pharma A/S is the larger company at $17B against $14B. Over the past year JAZZ returned +70% against +16% for ASND. The RyuScore puts JAZZ ahead, 48 against 9 out of 100.

Ascendis Pharma A/S and Jazz Pharmaceuticals plc compared on valuation, return and the RyuScore
FigureASNDJAZZ
Last close$229$218
Market cap$17B$14B
Trailing P/Elower is cheaper for the same earnings, not automatically bettern/a14.9
1-year return+16%+70%
5-year return+49%+62%
RyuScoresector-relative, 1–109/10048/100

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

Ascendis Pharma A/S

Revenue of $248M in Q4 2025, net income null.

Jazz Pharmaceuticals plc

Revenue of $1.2B in Q2 2026, net income $193M. Its largest reported line is Oncology, 31% of the disclosed total.

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