ASND vs JAZZ

Ascendis Pharma A/S and Jazz Pharmaceuticals plc, both Healthcare

Ascendis Pharma A/S is the larger company at $15B against $14B. Over the past year JAZZ returned +123% against +32% for ASND. Ryufin's sector-relative Smart Score puts ASND ahead, 8/10 against 6/10.

Ascendis Pharma A/S and Jazz Pharmaceuticals plccompared on valuation, return and Ryufin’s Smart Score
FigureASNDJAZZ
Last close$250$249
Market cap$15B$14B
1-year return+32%+123%
5-year return+108%+46%
Ryufin Smart Scoresector-relative, 1–108/106/10

Figures from SEC filings and end-of-day closes. Highlighting marks the higher or lower number, which is not the same as the better investment, a low P/E can be a warning and a high one can be deserved.

Ascendis Pharma A/S

Revenue of $248M in Q4 2025, net income null.

Jazz Pharmaceuticals plc

Revenue of $1.1B in Q1 2026, net income $293M. Its largest reported line is Oncology, 31% of the disclosed total.

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